University Hospitals Cleveland Medical Center

This study tests whether a community health worker acting as a personal coach can help Black children and teens better use their automated insulin delivery systems. Sixteen participants with higher-than-target blood sugar levels will receive monthly coaching for six months, follo…

This study aims to compare how two different types of replacement heart valves perform, especially during physical activity. Researchers will enroll 90 patients with severe aortic stenosis who are getting a valve replacement procedure called TAVR. Using special heart scans during…

This study compares two common surgical procedures for treating uterine prolapse to determine which one provides better results from the patient's perspective. Researchers will follow 320 women for three years after surgery, tracking complications, recovery, and quality of life. …

This study is testing a new surgical procedure for people with a severe leg circulation condition called chronic limb-threatening ischemia. For patients who have no other treatment options left and face amputation, this surgery aims to improve blood flow to help foot wounds heal.…

This study is testing a new system to help doctors in the emergency room prescribe antibiotics more carefully for suspected urinary tract infections (UTIs). It uses a prediction tool and follow-up calls to avoid giving antibiotics when they might not be needed. The goal is to fig…

This small pilot study is testing whether the herbal supplement milk thistle can help control fatty liver disease in children and young adults. Researchers want to see if it's easier for patients to take a supplement than to maintain strict diet and exercise changes. The study wi…

This study is comparing two surgical approaches for severe shoulder tears that cannot be fully repaired. Researchers are testing whether adding a newer procedure called superior capsular reconstruction (SCR) to a standard partial repair provides better pain relief and shoulder fu…

This study is testing whether a special graft made from processed North Atlantic cod skin can improve healing after gender-affirming vaginoplasty surgery. Researchers will enroll 20 transgender women undergoing this specific surgical technique to see how well the graft helps the …

This study is testing a self-management program designed to help adults with epilepsy better use their rescue medication to control breakthrough seizures. First, patients and caregivers will help design the program materials. Then, about 35 participants will try the 6-month progr…

This study is testing whether artificial intelligence (AI) software can help radiologists detect lung nodules on chest X-rays. The AI acts as a 'second reader' alongside radiologists, flagging potential nodules for review. Researchers will compare how often the AI and radiologist…

This study compares two different methods for diagnosing urinary tract infections (UTIs) in adults with symptoms. Participants are randomly assigned to have their UTI diagnosed using either the standard urine culture method or a newer DNA-based test called PCR. Researchers want t…

This study is testing whether checking blood pressure at home is a good way to diagnose high blood pressure in African American teenagers. Researchers will compare home readings to the current best method (a 24-hour wearable monitor) in 750 teens. The goal is to find a more conve…

This study aims to see if using a vaginal estrogen cream can improve sexual function for breastfeeding people after childbirth. It will compare the cream against a vaginal moisturizer in 100 participants over 12 weeks. Researchers will measure changes in sexual desire, comfort, a…

This study is testing if a digital health platform called Band Connect can help people stick to their at-home physical therapy exercises after shoulder surgery. Researchers want to see if better exercise compliance leads to less pain, faster recovery, and higher satisfaction for …

This study is testing if giving magnesium through an IV during a specific hip surgery helps reduce pain and the need for strong painkillers afterward. It will involve 64 adults who are already scheduled for this surgery. Researchers will compare pain levels and medication use bet…

This study is testing whether adding acupuncture to standard lifestyle advice helps women with chronic bladder pain feel better. Researchers want to see if six weeks of acupuncture improves pain scores more than just making lifestyle changes. The study is for women who haven't tr…

This study compares two implanted pain relief devices for people with chronic back pain after spine surgery. Participants first try temporary versions of both a spinal cord stimulator and a pain medication pump. They then choose which one worked better for them and can proceed wi…

This study is testing a specific nerve-blocking technique to see if it can better control pain and improve recovery for people having lower back fusion surgery. Researchers will place a small catheter in the back to deliver numbing medicine before surgery and track participants' …

This study aims to understand how people with bipolar disorder process information by tracking their eye movements. Researchers will measure how quickly participants look at emotional faces, how they respond to rewards, and their ability to control automatic eye movements. The go…

This study is testing a wearable sensor that measures oxygen levels in muscles. Researchers want to see if the data from this sensor can help them better understand how high school and college athletes recover from knee or hip surgery. The goal is to find better ways to decide wh…

This study is testing whether a specific teaching method called 'teach-back' helps patients remember their injury and treatment instructions after orthopedic trauma surgery. Researchers will compare patients who receive this education to those who don't, looking at how well they …

This study aims to compare two methods for recovering blood from sponges used during heart and lung surgeries: manual wringing by hand versus using an automated suction device. Researchers will measure how well each method preserves red blood cells and how much blood can be recov…

This study aims to understand if a blood test that measures recent alcohol use can help predict how patients recover after major surgery. Researchers will check this alcohol marker in adults who regularly drink and are having planned surgery with a hospital stay of at least three…

This study is testing whether short, easy-to-digest educational videos (called microlearning) can help patients feel more confident and recover better after same-day surgeries like vaginal hysterectomies or bladder sling procedures. Researchers will enroll 50 patients at Universi…