Solti Breast Cancer Research Group

This study tests whether a combination of two drugs (ribociclib and letrozole) can safely replace chemotherapy for people with a high-risk type of breast cancer (ER+/HER2-). About 1,100 participants will take the drugs before and after surgery. The goal is to see if those who res…

This study tests a combination of three drugs (atezolizumab, trastuzumab, and vinorelbine) in people with advanced HER2-positive breast cancer that has not responded to prior treatments. The goal is to see if this mix can shrink tumors better than current options, especially in c…

This study looks at tumor and blood samples from 180 people with metastatic cancer who have been treated with the drug trastuzumab deruxtecan (T-DXd). Researchers want to find a specific genetic marker that can predict how well a person will respond to the drug. The goal is to be…