Sarfez Pharmaceuticals, Inc.

This study tested whether a new extended-release version of the diuretic torsemide helps people with heart failure get rid of more salt (sodium) in their urine after lunch compared to the standard immediate-release version. Twenty adults with stable heart failure who were already…

This study tested whether a slow-release version of the water pill torsemide works better than the standard version at reducing urgent, frequent urination in people with chronic heart failure. 24 adults aged 50 and older with both conditions took each version for four weeks. The …

This study looked at how a new tablet combining two heart failure medicines (torsemide and spironolactone) is absorbed by the body. Twenty-four healthy adults took single doses of the combo pill, each drug alone, or both drugs together. The goal was to see if the combo works the …

This study tested whether taking a new extended-release pill (combining two heart medicines) with food changes how much medicine gets into the body. Twenty-four healthy adults took the pill once with food and once without, and researchers measured drug levels in blood and urine. …

This study looked at how a new extended-release tablet combining two heart failure medicines (torsemide and spironolactone) is absorbed and processed by the body. Twenty-four healthy adults took the drug and provided blood and urine samples over time. The goal was to measure drug…