Rise Therapeutics Llc

This trial tests an experimental oral treatment called R-3750, a live engineered bacterium designed to deliver a protein that may reduce gut inflammation. About 40 adults with active Crohn's disease will receive either R-3750 or a placebo capsule daily for 12 weeks. Researchers w…

This early-stage trial tests R-3750, a live biotherapeutic product, in 20 adults with late-stage acute respiratory distress syndrome (ARDS). The main goal is to see if it is safe and tolerable, while also checking for signs of improved lung function and less need for a ventilator…

This early-stage trial tests an oral probiotic called R-3750 in 27 people with mild-to-moderate COPD. The main goal is to see if it is safe and tolerable. Researchers will also check if it improves breathing and quality of life using a standard questionnaire. The study is not yet…

This early-stage trial will test an oral probiotic called R-2487 in 36 adults with Sjogren's syndrome. The main goal is to see if the probiotic is safe and tolerable. Researchers will also check for changes in disease activity and inflammation using blood and stool samples. The s…