Puretech
Clinical trials sponsored by Puretech, explained in plain language.
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New drug LYT-200 tested in patients with relapsed blood cancers
Disease control CompletedThis early-stage study tested a new drug called LYT-200 in 101 adults whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) had returned or stopped responding to treatment. The main goal was to check the drug's safety and find the right dose. Researchers …
Phase: PHASE1 • Sponsor: PureTech • Aim: Disease control
Last updated May 18, 2026 12:07 UTC
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Healthy volunteers help check for drug clashes in lung treatment combo
Knowledge-focused CompletedThis completed study tested 24 healthy adults to see how two drugs, deupirfenidone and nintedanib, interact when taken together. Researchers measured drug levels in the blood and watched for side effects over about 60 days. The goal was to gather safety and dosing information, no…
Phase: PHASE1 • Sponsor: PureTech • Aim: Knowledge-focused
Last updated May 26, 2026 10:01 UTC
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New lung drug candidate shows promise in early safety study
Knowledge-focused CompletedThis early-stage study tested a new drug called Lyt-100 (deupirfenidone) in 116 healthy adults aged 60-80. The goal was to compare its safety and how the body processes it versus the existing drug pirfenidone. Results will help decide the best dose for future studies in patients …
Phase: PHASE1 • Sponsor: PureTech • Aim: Knowledge-focused
Last updated May 26, 2026 09:57 UTC