Principia Biopharma, A Sanofi Company

This study tested an experimental oral drug called PRN1008 (rilzabrutinib) in 86 adults with immune thrombocytopenia (ITP) whose disease had returned or did not respond to other treatments. The goal was to see if the drug could safely raise platelet counts to reduce bleeding risk…

This study tested a new drug called rilzabrutinib, taken with steroids, to see if it is safe and can control IgG4-related disease, a rare condition where the body attacks its own tissues. About 27 adults with active disease took part. The goal was to see if the drug could prevent…

This study tested a new cream called PRN473 on 39 adults with mild to moderate eczema. Each person had two patches of eczema treated: one with the study cream and one with a placebo cream. The goal was to see if the cream is safe and helps reduce skin symptoms. The study lasted a…

This study looked at how taking a drug called rilzabrutinib with or without food, and in different pill forms, changes its levels in the blood. 24 healthy adults each took a single dose under different conditions. The goal was to gather information for future dosing, not to treat…