Princess Maxima Center For Pediatric Oncology

This study is for children and young adults up to age 21 whose leukemia or lymphoma has returned or not responded to standard treatment. It tests a combination of targeted drugs (dasatinib and venetoclax) plus chemotherapy to see if it is safe and effective. The goal is to contro…

This study is for children and young adults up to age 21 whose acute myeloid leukemia (AML) has come back or not responded to standard treatment. Researchers are testing a combination of two drugs—Vyxeos and clofarabine—to find the safest dose that can control the disease. The go…

This study tests a combination of the targeted drug trametinib with standard chemotherapy drugs (dexamethasone, cyclophosphamide, and cytarabine) in children and young adults up to age 21 whose leukemia or lymphoma has returned or not responded to treatment. The goal is to find t…

This study tests a drug called blinatumomab in infants under 1 year old who have a specific, hard-to-treat type of leukemia. The goal is to improve how long these babies stay cancer-free. About 160 infants will take part, and researchers will track their health over time.

This study tests a special fluorescent dye (anti-GD2-800CW) that makes neuroblastoma tumors glow during surgery. About 22 children aged 1 to 18 will receive the dye before their standard tumor removal surgery. The goal is to find a safe and effective dose so surgeons can better s…