Pediatric Brain Tumor Consortium

This study is testing a new combination treatment for children and young adults whose medulloblastoma or ependymoma brain tumors have come back. The main goal is to see if adding a targeted radiation treatment, delivered directly into the fluid-filled spaces of the brain, can hel…

This early-stage study is testing a new antibody drug called APX005M in children and young adults with brain tumors that have come back or stopped responding to standard treatments, or with a newly diagnosed, aggressive type of brain stem glioma. The main goal is to find the safe…

This study aimed to test a new treatment for children whose aggressive brain tumors had returned. The treatment involved injecting a specially engineered virus directly into the tumor, followed by a single low dose of radiation. The goal was to see if this combination could help …

This study is testing whether adding the drug hydroxychloroquine to two other targeted cancer drugs can better control brain tumors in children and young adults. It is for patients whose tumors have grown back or progressed despite previous similar treatments and who have specifi…