Pacira Pharmaceuticals, Inc

This study is for children under 6 years old who need heart surgery. It compares a long-lasting pain medicine called EXPAREL with a standard painkiller to see which works better and is safer. The goal is to improve pain control after surgery in young children.

This study tests a device called iovera® that uses cold to temporarily calm overactive nerves causing muscle tightness in the arm. About 132 adults with spasticity from a brain or spinal condition will get either the real treatment or a sham (fake) procedure. The goal is to see i…

This study tests if an injection called ZILRETTA can reduce pain in people with shoulder osteoarthritis. About 150 adults aged 50 to 80 will receive either ZILRETTA, a standard steroid, or a placebo. The main goal is to see if ZILRETTA improves daily pain scores after 12 weeks.

This study is a large registry that will follow 10,000 people with knee osteoarthritis to see how well different pain treatments work. Participants may receive injections, nerve blocks, or other therapies. The goal is to collect real-world data on pain relief, function, and side …