Nader Sanai

This early-stage study is testing a drug called niraparib for two types of aggressive brain cancer. It first checks if the drug reaches the tumor effectively after a short pre-surgery dose. If it does, participants can continue taking the drug, sometimes with radiation, to try to…

This study is testing whether an oral cancer drug called ribociclib can get into the brain and reach recurrent brain tumors. It involves 48 adults with recurrent high-grade glioma or meningioma who are scheduled for surgery. Patients take the drug for a short time before their op…

This early-stage study is testing whether a drug called quisinostat can effectively reach brain tumor tissue when given alongside standard radiation therapy. It is for adults with a specific, aggressive type of brain cancer called IDH-wildtype glioblastoma, either newly diagnosed…

This early-stage trial is testing a new drug called AZD1390 in combination with standard radiation therapy for adults with aggressive brain tumors (grade 4 glioma or glioblastoma). The study first checks if the drug successfully reaches the tumor tissue. Patients whose tumors sho…