Medtronic Cardiovascular

This study looks at how well the Medtronic Harmony Transcatheter Pulmonary Valve (TPV) works when used by doctors in everyday practice. It involves 150 people with certain heart defects who need a new pulmonary valve. The main goal is to see if the valve works properly and safely…

This study tests a special technique called the chimney graft for treating abdominal aortic aneurysms that have a short neck, making standard surgery risky. About 150 adults will receive this procedure using Medtronic's Endurant stent grafts. The goal is to see if the technique i…

This study is testing a new heart valve device (Evolut PRO) in 52 Chinese patients with severe aortic stenosis who are too high-risk for open-heart surgery. The valve is placed through a tube in the artery, avoiding major surgery. Researchers are checking how many patients surviv…

This study compares two types of replacement heart valves (self-expanding vs. balloon-expandable) in people with a small aortic valve opening and severe narrowing. About 1,100 participants will be followed to see which valve performs better in terms of survival, stroke, heart fai…

This study tests whether a less invasive heart valve replacement (TAVR) is safe and effective for people with moderate aortic stenosis, a condition where the heart's aortic valve is narrowed but not yet severe. About 650 participants will receive the Evolut TAVR system and be fol…

This study tests a new device called the Intrepid Transcatheter Mitral Valve Replacement System for people with severe mitral regurgitation (a leaky heart valve) who are too high-risk for open-heart surgery. The goal is to see if the device is safe and works well. About 128 parti…

This study compares two procedures—transcatheter aortic valve implantation (TAVI) and surgical valve replacement—in people with severe aortic stenosis who are at intermediate risk for surgery. About 1,700 participants were randomly assigned to one of the two treatments. The main …

This study looks at a less invasive procedure called TAVR to replace the aortic valve in people with a bicuspid (two-leaflet) valve that is severely narrowed. The goal is to see if it is safe and works well in patients who are at low risk for open-heart surgery. About 150 partici…

This study tests a less invasive procedure called TAVR against traditional open-heart surgery for people with severe aortic stenosis who are at low risk for surgery. About 2,200 participants will be followed for two years to see if TAVR is as safe and effective as surgery in prev…