Manchester University Nhs Foundation Trust

This trial tests whether adding interferon-gamma to standard antifungal medication can help people with chronic pulmonary aspergillosis, a progressive lung infection caused by the Aspergillus fungus. The study will include 50 adults starting antifungal treatment, who will be rand…

This study compares two recovery programs after rotator cuff repair surgery. One group follows standard care—wearing a sling for 6 weeks with limited movement. The other group starts moving sooner, guided by comfort rather than strict restrictions. Researchers will measure should…

This study looks at dental and jaw problems in children who had proton beam therapy for head and neck cancer. Researchers will survey survivors and review dental records to see how often these side effects occur and how they relate to radiation dose. The goal is to gather informa…

This study looks at whether women from different backgrounds have equal access to ambulance services during pregnancy, birth, and after having a baby. Researchers will analyze data from 18,000 women in Manchester, UK, comparing those who used an ambulance with those who didn't, a…

This study is following 10,000 adults who are having a heart MRI for medical reasons. Researchers want to see if the MRI results can help predict who will have heart problems in the future, like heart attacks or heart failure. The goal is to better understand how MRI scans can gu…

This study looks at how spasmodic dysphonia, a voice disorder causing uncontrollable vocal cord spasms, affects patients' jobs and social lives. Researchers will interview 20 adults who have received at least one botulinum toxin injection to understand if the treatment helps impr…

This study was designed to measure blood pressure in adults experiencing cardiac arrest and to see how a device called an impedance threshold device (ITD) affects it. The ITD is placed on the airway to help blood flow to the heart. However, the study was withdrawn before enrollin…