Loxo Oncology, Inc.

This study is testing whether a new oral drug called pirtobrutinib works better and is safer than the standard chemotherapy combination for people newly diagnosed with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). About 309 participants will be randomly …

This study is testing whether adding a new drug called pirtobrutinib to a standard two-drug combination works better for people with previously treated chronic lymphocytic leukemia or small lymphocytic lymphoma. About 600 participants will be randomly assigned to receive either t…

This study is comparing a new targeted drug called selpercatinib against standard treatments for advanced thyroid cancer that has a specific genetic change (RET mutation) and is getting worse. It involves adults (and some teens) whose cancer cannot be removed by surgery or has sp…