Jena University Hospital

This study compares two types of drug-coated balloons used to open blocked arteries in the leg due to peripheral artery disease. About 478 adults with moderate symptoms will be randomly assigned to receive either a sirolimus-coated or a paclitaxel-coated balloon. The main goal is…

This study compares a special balloon coated with sirolimus (a drug that helps keep arteries open) to a standard balloon for treating blocked arteries below the knee in people with peripheral artery disease. About 230 participants will be randomly assigned to one of the two treat…

This study tests whether MRI scans and blood tests can help doctors adjust treatment for locally advanced rectal cancer. About 40 participants will be monitored during chemotherapy and radiation to see if their tumors respond. The goal is to develop a non-invasive way to predict …