Jazz Pharmaceuticals

This study tested a drug called ZW25 in 87 people with advanced bile duct or gallbladder cancers that have a specific genetic change (HER2 amplification). The goal was to see if the drug could shrink tumors. Participants had already tried at least one other chemotherapy. The stud…

This study tested whether combining two drugs, zanidatamab and evorpacept (ALX148), is safe and can shrink tumors in people with advanced HER2-positive cancers that have spread or cannot be removed by surgery. A total of 52 adults took part. The main goals were to check for side …

This study tested a new drug called ZW25 (zanidatamab) combined with standard chemotherapy in 74 people with advanced HER2-positive cancers of the stomach, bile duct, or colon. The goal was to see if the combination is safe and can shrink tumors. While not a cure, the approach ai…

This study looked at 155 adults with narcolepsy who switched from a high-sodium medication (sodium oxybate) to a low-sodium version (Xywav). The goal was to see if their blood pressure changed. The results could help doctors and patients choose the best treatment for managing nar…

This study observed 272 adults with extensive-stage small cell lung cancer who were already receiving the drug Zepzelca as part of their routine care. Researchers tracked how well the drug shrank tumors and how long patients lived, while also monitoring side effects. The goal was…

This study tested an experimental drug called suvecaltamide in 169 adults with Parkinson's disease who still had moderate to severe shaking (tremor) despite their usual medications. The goal was to see if the drug could reduce tremor and improve daily activities like eating and d…

This study looked at whether adding EPIDIOLEX (a CBD-based medicine) to usual treatment can improve seizures and behavioral problems in people aged 1 to 65 with tuberous sclerosis complex (TSC). Researchers measured changes in behavior, sleep, quality of life, and seizure control…

This study looked at 113 adults in Italy with certain types of acute myeloid leukemia (AML) who were treated with Vyxeos liposomal as part of their normal care. Researchers tracked how many patients achieved complete remission without signs of leftover disease. The goal was to se…