Institute Of Hematology & Blood Diseases Hospital, China

This early-phase study tests a personalized cell therapy (CD19 CAR-T) in 15 adults with severe autoimmune diseases like lupus that have not responded to standard treatments. The therapy aims to reset the immune system by targeting and depleting faulty B cells, potentially reducin…

This study tests whether zoledronic acid, a drug usually used for bone health, can help people with a rare inherited blood disorder called congenital dyserythropoietic anemia (CDA). The goal is to see if it can raise hemoglobin levels and reduce the need for blood transfusions. O…

This study looks at whether getting a stem cell transplant right away is as good as getting some treatment first and then the transplant for people with higher-risk myelodysplastic syndrome (MDS). About 236 adults who are eligible for a transplant will be randomly assigned to one…

This study tests a new drug called CM336, a bispecific antibody, in 21 people newly diagnosed with a rare disease called AL amyloidosis. The goal is to see if the drug can improve blood markers of the disease and to check for side effects. Participants will receive the drug and b…

This study tests a treatment called BCMA-CART, sometimes combined with a stem cell transplant, in young adults (18-55) newly diagnosed with multiple myeloma. The goal is to see if it can make the cancer disappear or stay away longer. About 50 people will take part, and researcher…

This early-phase study tests a new treatment called CAR19-BCMA CAR-T for people with multiple myeloma that has come back or stopped responding to standard therapy. The therapy uses a patient's own immune cells, modified to attack two targets on cancer cells. The main goals are to…

This study looks at whether adding rituximab to the standard drug eltrombopag helps adults with immune thrombocytopenia (ITP) who haven't responded well to past treatments. About 224 participants will be randomly assigned to get either eltrombopag alone or eltrombopag plus rituxi…

This study tests a combination of low-dose chemotherapy and immune-targeted drugs in adults newly diagnosed with a specific type of leukemia (Ph-negative B-cell ALL). The goal is to see if this gentler approach can achieve deep remission (no cancer cells detectable) and improve s…

This study tests a drug called orelabrutinib in people with marginal zone lymphoma who have not had any prior treatment. The goal is to see if the drug can shrink or control the cancer. About 30 adults will take the pill and be monitored for side effects and how well the cancer r…

This study tests a new treatment plan for people newly diagnosed with primary plasma cell leukemia, a rare and aggressive blood cancer. The approach combines standard chemotherapy drugs with two rounds of CAR T-cell therapy and a stem cell transplant. The goal is to see if this i…

This study is a large registry that will follow 2,300 people in China with various blood diseases, such as leukemia, multiple myeloma, and hemophilia. Researchers will collect information from medical records to understand how common these diseases are, what treatments people rec…

This study looks at growth problems in children and teens with thalassemia, a blood disorder. Researchers will check physical development, hormones, nutrition, and brain function. They will then provide a program of monitoring, education, diet plans, exercise, and support to see …

This study watches children and teens with blood cancers who get a serious fungal infection despite taking prevention drugs. Researchers want to see if a medicine called L-AmB works as well and is safer for kids compared to adults. The goal is to gather real-world data to improve…