Institut De Recherches Internationales Servier

This study tests a daily pill (ivosidenib) against a standard shot (azacitidine) in 48 adults with a specific genetic form of myelodysplastic syndromes (MDS) who haven't had prior treatment. The goal is to see which better controls the disease by improving blood counts and reduci…

This study tests a new combination of drugs (ivosidenib, durvalumab, and chemotherapy) as a first treatment for people with advanced bile duct cancer that has a specific IDH1 gene mutation. The goal is to see if the combination is safe and shrinks tumors. About 52 adults with ino…