Insmed Incorporated

This study tested an experimental pill called brensocatib in 29 adults with cystic fibrosis. The main goals were to see how the drug behaves in the body and whether it is safe compared to a placebo over 4 weeks. Participants took the pill once daily, and researchers measured drug…

This study tested an inhaled powder called treprostinil palmitil (TPIP) in 102 adults with pulmonary arterial hypertension (PAH), a condition where high blood pressure in the lungs makes it hard to breathe. Participants received either TPIP or a placebo for 16 weeks. The main goa…

This study tested a once-daily pill called brensocatib in 1,767 adults with non-CF bronchiectasis, a lung condition that causes chronic cough and frequent infections. The goal was to see if the drug could reduce the number of serious lung flare-ups (pulmonary exacerbations) over …

This study looked at the long-term safety of an inhaled medication called treprostinil palmitil (TPIP) for people with pulmonary hypertension caused by interstitial lung disease. Thirty-one adults who completed a previous study took part. The main goal was to check for side effec…

This study tested whether adding an inhaled antibiotic (ALIS) to standard oral antibiotics helps adults with a new diagnosis of a hard-to-treat lung infection caused by MAC bacteria. About 425 adults took part. The main goal was to see if the combination improved breathing sympto…

This study tested an experimental drug called brensocatib in 288 adults with long-term sinus inflammation but no nasal polyps. Participants took either 10 mg, 40 mg, or a placebo daily for 24 weeks. The goal was to see if the drug could improve daily symptoms like congestion, run…

This study tested two different versions of an inhaled drug (TPIP) in 42 healthy adults to see how much of the drug gets into the blood. Participants inhaled a single dose of each version on separate days. The results help researchers understand which formulation works better for…