Insmed Incorporated

This large Phase 3 trial tested whether a daily pill called brensocatib could reduce the frequency of serious lung flare-ups in people with bronchiectasis, a chronic lung disease. Over 1,700 participants took either the drug or a placebo for one year to see if it lowered their ra…

This study tested whether an inhaled powder called treprostinil palmitil could help people with pulmonary arterial hypertension (PAH), a serious condition affecting blood vessels in the lungs. Over 100 adults with PAH who were already on stable medication were randomly assigned t…

This study tested whether a daily pill called brensocatib could reduce symptoms and sinus inflammation in adults with long-term sinusitis who don't have nasal polyps. For 24 weeks, 288 participants took either brensocatib at one of two doses or a placebo pill, while continuing th…

This study tested whether adding a new inhaled antibiotic (ALIS) to standard oral medications works better than the standard medications alone for adults newly diagnosed with a MAC lung infection. It involved 425 adults and measured whether the combination improved breathing symp…

This study tested a new oral drug called brensocatib in adults with cystic fibrosis. The main goals were to see how the drug moves through the body and to check its safety over 4 weeks. A small group of 29 participants took either the drug or a placebo (a pill with no medicine) o…

This study aimed to compare how two different powder formulations of the drug treprostinil are absorbed into the body when inhaled. It involved 42 healthy volunteers who each tried different strengths of the two inhaler versions. The main goal was to measure drug levels in the bl…