Hoffmann-la Roche

This study tested whether giving two immunotherapy drugs (tiragolumab and atezolizumab), with or without standard chemotherapy, before and after surgery could help people with early-stage, operable lung cancer. The goal was to see if this approach was safe, could shrink tumors be…

This study aimed to see if a daily pill called pralsetinib works better than standard chemotherapy as the first treatment for people with advanced lung cancer that has spread and has a specific genetic change called a RET fusion. It involved 223 participants worldwide who had not…

This early study tested a new drug called RO7565020 to see if it's safe for people with chronic hepatitis B. Researchers gave the drug to 60 healthy volunteers and hepatitis B patients to check for side effects and how the body processes it. The study was terminated after this in…

This study tested whether adding the immunotherapy drug atezolizumab to the targeted therapy cabozantinib works better than cabozantinib alone for people with advanced kidney cancer. It was for patients whose cancer had started growing again after a previous type of immunotherapy…

This study tested an experimental drug called basmisanil in children aged 2 to 14 with Dup15q syndrome, a rare genetic disorder that causes developmental delays, seizures, and learning difficulties. The main goal was to see if the drug could safely improve daily living skills, co…

This study aimed to see if digital health tools, like smartphone apps, could help cancer patients better manage their symptoms and improve their quality of life while receiving standard drug treatments. It involved 49 participants with specific types of lung or liver cancer. The …