Hôpital Le Vinatier

This study tests whether training mental health professionals to deliver a short psychoeducational program (BREF) can reduce the burden on caregivers of people with schizophrenia or first psychotic episode. The trial will include 206 caregivers, comparing those who receive the pr…

This study tests a non-drug treatment called transcranial direct current stimulation (tDCS) for depression with catatonia in adults with Down syndrome. 62 participants will receive either real or fake tDCS for 15 sessions. Researchers will measure changes in symptoms, safety, and…

This study tests a new psychoeducation program led by an advanced practice nurse to reduce the burden on family caregivers of young adults (ages 18-35) who have had a first psychotic episode. The program includes individual and group sessions to support caregivers. Researchers wi…

This study aims to create a French-language memory task that can be used during brain scans to measure source-monitoring—the ability to remember where information came from. Researchers will test the task on 120 people, including those with schizophrenia and healthy volunteers. T…

This study looks at how early-life trauma changes the way the brain releases dopamine when smelling pleasant odors. Researchers will use brain scans to compare 15 adults with a history of trauma and 15 without. The goal is to understand the link between trauma, smell perception, …

This study tests whether a program combining peer support (someone with lived experience of mental health issues) and a 'Hope Box' (a box filled with personal items that bring comfort and hope) can help people hospitalized after a suicide attempt. About 40 patients will receive t…

This study looks at how the brain processes time and attention after losing a loved one to suicide, homicide, or accident. Researchers will measure brain waves in 61 adults who experienced such a loss recently. The goal is to find early signs that may lead to PTSD or depression, …

This study looks at how dopamine, a brain chemical, influences our ability to remember whether something really happened or was just imagined. Researchers will give healthy volunteers either a dopamine-boosting drug, a dopamine-blocking drug, or a placebo, then test their memory.…

This study aims to find out how many homeless people in France have autism, ADHD, or intellectual disability. Researchers will screen and diagnose 150 homeless adults living in shelters. The results could help create better support services for this group.

This study is testing whether a 3-day training program called REFOCUS can help mental health teams better support recovery in people with severe mental disorders like schizophrenia or bipolar disorder. About 760 patients aged 15 to 65 will take part. The main goal is to see if th…

This study looks at how adults with intellectual developmental disorder (IDD) understand emotions, compared to people without IDD. Researchers will test 60 adults using tasks that involve recognizing facial expressions, emotions in context, and vocal tones. The goal is to find sp…

This study follows 32 adults with cocaine use disorder during inpatient detox to track how their sleep changes from active use through withdrawal. Using wearable devices and hormone tests, researchers measure both objective and subjective sleep quality. The goal is to understand …