Grupo Español Multidisciplinar De Melanoma

This study tests a combination of two drugs, enfortumab vedotin and pembrolizumab, in people with advanced melanoma that has worsened after standard treatments. The goal is to see if this combo can shrink tumors. About 60 adults with unresectable stage III or IV melanoma will tak…

This study tests a two-step treatment for people with advanced melanoma that has spread to the brain and is causing symptoms. First, patients take two targeted pills (encorafenib and binimetinib) for about 8 weeks, then switch to two immunotherapy drugs (cemiplimab and fianlimab)…

This study tests a drug called tebentafusp in people with a rare eye cancer (uveal melanoma) that has spread to the liver but not elsewhere. The goal is to see if giving the drug before surgery can completely eliminate the cancer in the liver. About 19 participants will receive t…