Fundación Para La Investigación Del Hospital Clínico De Valencia

Researchers compare three ovulation trigger approaches in women with low ovarian reserve undergoing fresh IVF cycles. Participants receive either human chorionic gonadotropin (hCG) alone, follitropin delta plus hCG, or a dual trigger using a GnRH agonist plus hCG. The trial measu…

Researchers are testing whether sodium zirconium cyclosilicate (Lokelma) controls high potassium better than the usual approach of reducing or stopping RAASi and MRA medicines in people with chronic kidney disease. The trial enrolls adults with potassium levels between 5.0 and 6.…

This trial compares a new powered circular stapler with standard manual staplers in patients having colorectal surgery. The goal is to see if the powered device reduces anastomotic leakage, a serious complication where the reconnected bowel leaks. Researchers will randomly assign…

This study tests whether a potassium-lowering drug called sodium zirconium cyclosilicate (Lokelma) can help elderly patients with heart failure and chronic kidney disease safely take higher doses of RAASi medications, which are often limited by high potassium levels. The trial wi…

Researchers are testing whether a 3D imaging model called 3D-PANC MSP is better than standard CT scans at showing how pancreatic tumors respond to chemotherapy before surgery. The study includes 70 patients with borderline or locally advanced pancreatic adenocarcinoma who have re…

This study is testing whether a single intravenous dose of iron can improve quality of life and reduce frailty in adults aged 65 and older who have iron deficiency after a heart attack. About 538 participants will be randomly assigned to receive either the iron infusion or standa…

This study looks at whether a pacemaker can improve exercise ability and quality of life in people with heart failure with preserved ejection fraction (HFpEF) who also have a small heart chamber and a low heart rate during activity. About 30 participants will get a pacemaker and …

Researchers are investigating how mitochondria, the energy-producing structures inside muscle cells, relate to frailty in older adults. The study includes about 120 people: older adults with type 2 diabetes, healthy older adults, and healthy young adults. Everyone does a six-week…