Epizyme, Inc.

This study tested a new drug called tazemetostat combined with standard chemotherapy (doxorubicin) for people with advanced epithelioid sarcoma, a rare cancer of the soft tissues. The trial had two parts: first to find a safe dose, then to see if the combination helped people liv…

This study tested a new drug, tazemetostat, combined with standard hormone therapies (enzalutamide or abiraterone/prednisone) in men with a hard-to-treat type of advanced prostate cancer that had stopped responding to hormone therapy. The goal was to find the best dose and see if…

This study looked at how the drug tazemetostat is absorbed and processed in people with advanced cancer who also have moderate or severe liver problems. Researchers compared these participants to those with normal liver function. The goal was to understand safety and drug levels …