Dompé Farmaceutici S.p.a

This study tested an eye drop called OXERVATE in 37 adults with stage 1 neurotrophic keratitis, a condition where the cornea loses feeling and doesn't heal properly. The treatment was given for 8 weeks, and patients were followed for 24 weeks to see if the cornea healed. The goal…

This study tested a medicated eye drop called cenegermin (Oxervate) in 85 adults with severe dry eye caused by Sjogren's syndrome, who were already using another eye drop (cyclosporine). The goal was to see if cenegermin could increase tear production and reduce dry eye symptoms …

This study looked at the long-term safety and effectiveness of OXERVATE eye drops in 24 people with stage 1 neurotrophic keratitis, a rare eye condition that can damage the cornea. Participants had already completed the DEFENDO study. Researchers checked if the cornea stayed heal…

This study tested a drug called reparixin in 66 adults with severe acute respiratory distress syndrome (ARDS) who were on breathing machines. The goal was to see if adding reparixin to standard care could improve lung function and reduce time on the ventilator. The trial compared…

This study tested a new eye drop containing a natural protein (rhNGF) to see if it can safely relieve symptoms of dry eye disease. 317 adults with moderate-to-severe dry eye used the drops or a placebo for 4 weeks. The goal was to measure improvements in eye discomfort and tear p…