Deciphera Pharmaceuticals, Llc

This study tests a new drug, ripretinib, against the current standard sunitinib for people with advanced gastrointestinal stromal tumor (GIST) that has a specific genetic change and has stopped responding to the first treatment, imatinib. About 54 adults will be randomly assigned…

This study tests an experimental drug called vimseltinib for people with tenosynovial giant cell tumor (TGCT), a rare, non-cancerous growth in the joints that can't be removed surgically. About 123 adults with moderate to severe pain or stiffness will receive either the drug or a…

This study tests an experimental drug called vimseltinib in people with a rare joint tumor (TGCT) or advanced solid tumors. The goal is to find the safest dose and see if it shrinks tumors or improves joint movement. About 120 adults will take part in two phases: first to check s…