Chiesi Farmaceutici S.p.a.

This study tested whether a new inhaler (CHF 1535) works as well as a standard one (Symbicort) for people with chronic obstructive pulmonary disease (COPD). About 750 Chinese adults aged 40 and older with moderate-to-severe COPD took part. The main goal was to compare changes in …

This study tested two ways of using the Foster inhaler in 1714 adults with asthma that was not fully controlled. One group used Foster both as a daily maintenance treatment and as needed for relief, while the other group used Foster daily plus a separate salbutamol inhaler for re…

This study looked at the long-term safety and effectiveness of a drug called pegunigalsidase alfa for adults with Fabry disease, a rare genetic condition that can damage organs. The 29 participants had already completed a previous study and received the drug every 4 weeks. Resear…

This study tested whether adding an extra medication (glycopyrrolate) to a standard asthma inhaler (QVAR) helps people whose asthma is not well controlled. 98 adults with asthma took either the combination or a placebo for 6 weeks. Results showed that the combination improved lun…

This study tested a new inhaler (CHF 1535) that combines two medicines—a steroid and a long-acting bronchodilator—against a standard steroid-only inhaler in 542 adults with asthma that wasn't well controlled. The goal was to see if the combination improved morning lung function m…

This study looked at how well the Trimbow inhaler works for people with COPD when used in real-world conditions, not just in a lab. Over 12 weeks, 362 adults aged 40 and older used the inhaler, which combines three medicines to open airways and reduce inflammation. The main goal …

This study tested a new propellant (HFA-152a) that is better for the environment in a common asthma inhaler. 827 adults with moderate to severe asthma used either the new or the current inhaler for 12 weeks. The goal was to see if the new version is as safe and works just as well…

This study tested whether a combination inhaler (containing both an anti-inflammatory steroid and a fast-acting bronchodilator) works better than a steroid-only inhaler for adults with asthma. Over 1,300 participants on medium or high doses of inhaled steroids took part. The goal…

This study tested whether adding a drug called glycopyrrolate to a standard asthma inhaler (Foster) helps people whose asthma is not well controlled with their current medications. 211 adults with uncontrolled asthma took part. The main goal was to see if the combination improved…

This study tested whether switching from a standard two-drug inhaler to a new three-drug inhaler (CHF5993) could improve lung function in 25 people with advanced COPD. Researchers used special imaging to measure airway volume and airflow. The goal was to see if the new inhaler wa…

This study looked at the long-term safety of a drug called pegunigalsidase alfa for adults with Fabry disease, a rare genetic disorder. A total of 97 people who had completed earlier studies received the drug through an IV every two weeks. The main goal was to track any side effe…

This study tested a new inhaler that combines three medicines (CHF 5993) against a two-medicine inhaler (CHF 1535) in over 3,400 adults with COPD. The goal was to see if the triple therapy improves lung function and reduces serious breathing attacks over one year. Participants us…

This study looked at whether the color of an asthma inhaler (pink vs. white) affects how people perceive their asthma symptoms. 78 adults with moderate to severe asthma used both colored inhalers and rated their symptoms. The goal was to see if the device color influences symptom…

This early-stage study tested an inhaled drug called CHF10073 in 155 healthy volunteers to see if it is safe and how the body processes it. The study also checked how another drug, itraconazole, affects CHF10073 levels. The goal was to gather safety information before testing the…

This study looked at how much of the asthma drug CHF 6001 gets into the blood of teenagers compared to adults after a single dose. It involved 50 people with asthma. The goal was to understand the drug's behavior, not to test if it works or helps symptoms.

This study looked at 1,005 people having emergency heart treatment (acute coronary syndrome) who received a stent and were given the blood thinner cangrelor. Researchers tracked how often bleeding occurred within 30 days when patients switched from cangrelor to other common blood…

This study in 30 healthy adults aims to see if cyclosporine changes how the body absorbs CHF6001, a potential COPD treatment. Participants take CHF6001 alone first, then with cyclosporine, and blood samples are compared. The goal is to understand drug interactions, not to treat a…