Centre Francois Baclesse

This study tests whether a web application can help breast cancer patients better follow their hormone therapy and improve their quality of life. About 438 patients starting hormone therapy after breast cancer treatment will use the app or receive standard care. The main goal is …

This study tests whether adding the drug olaparib to standard radiation and chemotherapy can help people with aggressive, inoperable brain tumors live longer. About 91 participants will receive the combination treatment. The goal is to find the best dose and see if it improves su…

This study tests a newer radiation method (SIB-IMRT) combined with chemotherapy for people with advanced anal cancer. The goal is to see if this approach can reduce the need for treatment breaks while still controlling the cancer. About 71 adults with locally advanced anal cancer…

This study aimed to test a new treatment for people whose cancer returned after previous radiation therapy. The approach combined special nanoparticles injected into the blood with targeted proton therapy to try to control the tumor. The study was withdrawn before any participant…

This study looks at women who have recovered from rare ovarian cancers (germ cell or sex cord-stromal tumors) to understand how chemotherapy affects their long-term health and daily life. Researchers will compare those who had chemotherapy plus surgery with those who had surgery …

This study examines head and neck cancers that happen during pregnancy or within a year after giving birth. Researchers will check for viruses like HPV and EBV, look at pregnancy complications, and describe tumor types. The goal is to better understand these rare cases, not to te…

This study looks at whether adding a weekly check by a specially trained radiation technologist (MERM) to the usual doctor visits can help find side effects from proton therapy more often. About 92 adults with brain or upper throat tumors will take part. The goal is to see if thi…

This study looks at how to better support women who have finished treatment for ovarian or endometrial cancer. Researchers will assess patients' needs for supportive care and create a personalized plan to help manage long-term side effects. The goal is to improve quality of life …