Calico Life Sciences Llc

This early-phase study tests a new drug, ABBV-CLS-484, alone or combined with other cancer treatments, in people with advanced solid tumors that have not responded to standard therapy. The goal is to find a safe dose and see if the drug can shrink tumors. About 248 adults with ce…

This study tests an experimental drug called fosigotifator in people with Vanishing White Matter disease, a rare genetic brain disorder. About 50 adults, children, and infants will receive the drug to see if it is safe and how the body processes it. Researchers will also look for…