Bristol-myers Squibb

This study tests an experimental drug, BMS-986504, in people with advanced solid tumors that have a missing MTAP gene. The drug is given alone or with other cancer treatments to see if it can shrink tumors and how safe it is. About 260 adults with various cancers (like lung or pa…

This early-stage study tests a new drug called BMS-986528 in 84 adults with rheumatoid arthritis that hasn't responded to standard treatments. The main goals are to check safety and how the drug moves through the body, while also looking for signs it might reduce disease activity…

This study tests a combination of two immunotherapy drugs (nivolumab and relatlimab) in 30 people in India with advanced melanoma that has not been treated before. The main goal is to check safety and side effects, and also to see how well the drugs shrink tumors. Participants mu…

This study looks at the long-term safety of a drug called admilparant in people with pulmonary fibrosis (lung scarring). About 2,277 adults who finished earlier studies will take part. The goal is to see if the drug is safe to take over a longer period, not to cure the disease.

This early-stage study aims to check the safety and how the body processes a new experimental drug called BMS-986454 in people with rheumatoid arthritis. It will involve 46 participants who have arthritis that didn't fully respond to standard methotrexate treatment. Researchers w…

This study tests whether a combination of two drugs, KarXT and KarX-EC, can safely reduce irritability in children and teenagers (ages 5 to 17) with autism spectrum disorder. About 176 participants will receive either the study drug or a placebo for 8 weeks. The main goal is to s…

This study tests whether a new medication, KarXT plus KarX-EC, can reduce irritability in children and teens (ages 5 to 17) with autism. About 176 participants will receive either the drug or a placebo for 8 weeks. The main goal is to see if the drug improves irritability scores …

This early-stage study aims to understand how the experimental drug BMS-986435 behaves in people with normal liver function compared to those with mild or moderate liver impairment. Researchers will measure drug levels in the blood and monitor safety. The study involves 24 adults…

This study follows about 1,200 pregnant women with ulcerative colitis who take the drug ozanimod. Researchers will track the health of mothers and babies, looking for birth defects and other problems. The goal is to learn whether the drug is safe to use during pregnancy.

This study is a registry that will gather information from about 500 adults in Asia who have been diagnosed with myelodysplastic syndromes (MDS). The goal is to learn more about the patients' backgrounds, the treatments they receive, and how their disease progresses over time. No…

This observational study follows about 10 Korean patients with advanced ROS1-positive lung cancer or NTRK fusion solid tumors who are already receiving the drug repotrectinib as part of routine care. Researchers will track side effects and tumor response over up to 12 months to u…