Astellas Pharma Inc

This study is for people in Japan aged 40 and older with geographic atrophy, a form of age-related macular degeneration that causes vision loss. The goal is to check the safety of a monthly eye injection called ASP3021 over 12 months. About 20 participants will receive the inject…

This study monitors the safety and effectiveness of peficitinib, a medication for rheumatoid arthritis (RA), in 3,000 patients receiving it for the first time in regular medical practice. Researchers will track side effects, infections, and disease activity scores to see how well…

This early-phase study tests a new drug, ASP3082, in people with advanced solid tumors that have a specific genetic change called KRAS G12D. The study aims to find safe doses of ASP3082, given alone or with another drug (cetuximab). About 681 participants will receive the treatme…

This study tests a new drug, ASP5834, for people with advanced solid tumors that have certain changes in the KRAS gene. The drug is given alone or with another drug (panitumumab) for colorectal cancer. The main goals are to find a safe dose and check for side effects. About 364 a…

This study tests a new drug, ASP2246, for adults who have trouble moving after a stroke. It is the first time this drug is used in humans. The study has two parts: first, finding safe doses by giving the drug directly to the brain during surgery; second, comparing the drug to a s…