Agenus Inc.

This study tests whether adding botensilimab, an immune-boosting drug, to standard chemotherapy helps people with metastatic pancreatic cancer live longer without their cancer growing. It includes 81 adults whose cancer got worse after initial treatment. Participants are randomly…

This early-stage study tests two experimental drugs (botensilimab and balstilimab) that help the immune system fight cancer. It includes about 500 adults with advanced solid tumors like lung, ovarian, or colorectal cancer that haven't responded to standard treatments. The main go…

This study tests a new drug called botensilimab, alone or with another drug, in 150 people with advanced melanoma that stopped responding to prior immunotherapy. The goal is to see if the drug can shrink tumors or slow the cancer's growth. Participants must have had prior anti-PD…

This phase 2 study tests two experimental immunotherapy drugs, botensilimab alone or combined with balstilimab, against standard chemotherapy options for people with advanced colorectal cancer that has stopped responding to previous treatments. The goal is to see if these drugs c…