Actelion

This study tested a medication called macitentan in children with pulmonary arterial hypertension (PAH), a serious condition causing high blood pressure in the lungs. It compared the drug to standard care to see if it was safe, worked well in children's bodies, and could help con…

This study tested if a single pill combining two existing medicines (macitentan and tadalafil) works better for controlling pulmonary arterial hypertension (PAH) than taking the medicines separately. It involved 187 adults with PAH and compared the combination pill against the in…

This study tested an experimental oral medication called ACT-293987 for adults with pulmonary arterial hypertension (PAH), a serious lung and heart condition. Participants received either the drug or a placebo twice daily for 21 weeks to see if it improved blood flow in their lun…

This large, completed Phase 3 trial tested whether a new oral medication called selexipag could safely delay serious health events or death in adults with pulmonary arterial hypertension (PAH), a severe lung blood vessel disease. The study involved over 1,150 patients and compare…