X-linked protoporphyria (XLP)
Clinical trials for X-linked protoporphyria (XLP) explained in plain language.
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A pill that could let people with rare sunlight disorder step outside without pain
Disease control Recruiting nowResearchers are testing an oral drug called PORT-77 in people with erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP), rare conditions that cause severe pain after sunlight exposure. The trial enrolls about 225 adults and adolescents aged 12 and older. It compa…
Matched conditions: X-LINKED PROTOPORPHYRIA (XLP)
Phase 2/3 • Sponsor: Portal Therapeutics, Inc. • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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New hope for rare sun allergy: bitopertin offered to patients with no options
Disease control Expanded accessThis expanded access program provides bitopertin (DISC-1459) to patients aged 12 and older with erythropoietic protoporphyria (EPP) or X-linked protoporphyria (XLP) who have no satisfactory treatment options in the US. The goal is to offer access and gather safety information. Pa…
Matched conditions: X-LINKED PROTOPORPHYRIA (XLP)
Sponsor: Disc Medicine, Inc • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC