WILLIAMS SYNDROME
Clinical trials for WILLIAMS SYNDROME explained in plain language.
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Could a common allergy drug boost brain power in kids with williams syndrome?
Disease control CompletedThis study tested a drug called clomastine fumarate in 28 children aged 3-12 with Williams syndrome, a genetic condition that causes developmental delays. The goal was to see if the drug could improve thinking, movement, and social skills by repairing brain myelin. The study used…
Matched conditions: WILLIAMS SYNDROME
Phase: PHASE2 • Sponsor: Qilu Hospital of Shandong University • Aim: Disease control
Last updated Jun 08, 2026 13:13 UTC
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PET scans reveal how the brain thinks in health and disease
Knowledge-focused CompletedThis study used PET scans to measure blood flow in the frontal lobe while participants performed thinking tasks. It included healthy volunteers and people with schizophrenia or Parkinson's disease. The goal was to understand how the frontal lobe works during cognitive activities …
Matched conditions: WILLIAMS SYNDROME
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:59 UTC
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NIH study probes hidden impact of stiff arteries in rare genetic condition
Knowledge-focused CompletedThis study looked at how blood vessel stiffness affects organs like the heart, brain, kidneys, and gut in people with Williams Syndrome (WS) or supravalvular aortic stenosis (SVAS). Researchers compared 159 participants (ages 3–85) with these conditions to healthy volunteers over…
Matched conditions: WILLIAMS SYNDROME
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:57 UTC
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Stretchy skin may reveal heart risks in rare genetic condition
Knowledge-focused CompletedThis study looked at how stretchy the skin and blood vessels are in people with Williams syndrome, a genetic condition that can cause heart problems. Researchers measured skin and pulse speed in 43 participants aged 5 to 70. The goal was to learn how these tissues change over tim…
Matched conditions: WILLIAMS SYNDROME
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:08 UTC
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Scientists launch DNA bank to unlock secrets of rare heart and genetic conditions
Knowledge-focused CompletedThis study collected DNA, tissue, and medical history from 305 people with Williams syndrome or supravalvar aortic stenosis (SVAS), as well as their family members and healthy volunteers. The goal was to create a resource for future research to understand why symptoms vary so muc…
Matched conditions: WILLIAMS SYNDROME
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:08 UTC