Who grade 3 glioma
Clinical trials for Who grade 3 glioma explained in plain language.
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Targeted drug shows promise for Hard-to-Treat brain and bile duct cancers
Disease control OngoingThis study tests a drug called olaparib in people with advanced cancers (like brain tumors, bile duct cancer, or other solid tumors) that have a specific gene change called IDH1 or IDH2 mutation. The drug works by blocking an enzyme that cancer cells need to grow. About 89 partic…
Matched conditions: WHO GRADE 3 GLIOMA
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Brain radiation showdown: proton vs. photon – which saves your mind?
Disease control OngoingThis study compares two radiation methods—proton beam and photon beam (IMRT)—in 120 people with slow-growing brain tumors (IDH-mutant gliomas). The goal is to see which better preserves memory and thinking over time. Participants are randomly assigned to one type of radiation and…
Matched conditions: WHO GRADE 3 GLIOMA
Phase 2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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New drug combo shows promise for kids with aggressive brain tumors
Disease control OngoingThis phase 2 trial tests whether two targeted drugs, dabrafenib and trametinib, can improve outcomes for children and young adults with a specific type of high-grade glioma (BRAF V600-mutant) after they receive radiation therapy. The study enrolls 58 participants aged 25 or young…
Matched conditions: WHO GRADE 3 GLIOMA
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC