Venous leg ulcer (VLU)

This trial is testing whether adding a special wound matrix (OCM) to standard compression and routine care helps heal venous leg ulcers better than standard care alone. Adults with a venous leg ulcer will be randomly assigned to receive either the OCM plus standard care or standa…

This phase 2 trial tests a gel called EscharEx, made from pineapple enzymes, on people with venous leg ulcers that have stubborn dead tissue. The gel is applied to the wound to break down and remove non-viable tissue, potentially speeding up healing. The study involves 20 adults …

This study compares two types of compression bandages for treating venous leg ulcers, which are slow-healing wounds on the lower leg. About 386 adults will receive either the new Mepi Press 2 or the standard UrgoK2 bandage for up to 12 weeks. The goal is to see if the new bandage…

This study tests a new 'smart bandage' that checks wound moisture, temperature, and acidity, then sends updates to a nurse's app. About 110 adults with hard-to-heal leg ulcers will either get the smart bandage plus standard care or standard care alone. The goal is to see if the s…

This study compares Vashe solution, a wound cleanser, to standard saline for treating leg ulcers that show signs of heavy bacterial infection. About 102 adults with venous or mixed leg ulcers will be randomly assigned to one of the two solutions. The goal is to see if Vashe reduc…

This study tests a new system called Tight Alright that uses a small wearable device under bandages to measure pressure on leg ulcers. The device sends real-time pressure data to a mobile app and healthcare team, helping ensure the right pressure is applied for healing. About 40 …