VASOMOTOR SYMPTOMS

This phase 3 trial tested whether a hormone called estetrol (E4) can reduce the frequency and severity of moderate to severe hot flashes in women going through menopause. Over 1,000 women took either 15 mg, 20 mg, or a placebo daily for 12 weeks. The study measured changes in hot…

This early-stage study tested the safety of a new drug called MT-8554 in 24 women who have frequent hot flashes (at least 7 per day). The goal was to see if the drug is safe and how the body processes it. Participants included women with breast cancer or those going through menop…

This study tested whether a daily dietary supplement called Bonafide-HF3.0 could reduce hot flashes and night sweats in women aged 40 to 70 going through menopause. Over 100 women took the supplement for 4 weeks, with an optional 8-week extension. Researchers tracked the number a…

This study tracked 20 women aged 35–50 who had a hysterectomy but kept at least one ovary. Researchers wanted to see how often and how bothersome hot flashes, night sweats, and related symptoms were right after surgery. Participants filled out surveys before and two weeks after t…

This study looked at how well new pill forms of elinzanetant are absorbed by the body compared to the original soft gel capsule. Eighteen healthy women aged 18-65 took single and multiple doses of different pill versions. Researchers measured drug levels in the blood and checked …