Uncontrolled hypertension
Clinical trials for Uncontrolled hypertension explained in plain language.
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Neck implant aims to tame stubborn high blood pressure
Disease control CompletedResearchers are studying the long-term safety and effectiveness of the Barostim Neo System in people with uncontrolled high blood pressure who already received the implant. Participants continue their usual blood pressure medications while the device stimulates nerves in the neck…
Matched conditions: UNCONTROLLED HYPERTENSION
Sponsor: CVRx, Inc. • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Can a new pill tame blood pressure that Won't budge?
Disease control CompletedThis trial tests an experimental pill called SAL0120, taken once a day, in adults whose blood pressure stays high even when they already take two or more blood pressure medicines. About 256 people aged 18 to 75 with uncontrolled or resistant hypertension will receive either a low…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase 3 • Sponsor: Shenzhen Salubris Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Aug 29, 2026 00:00 UTC
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New drug baxdrostat aims to tame stubborn high blood pressure
Disease control CompletedThis Phase 3 trial tested a daily pill called baxdrostat in about 800 adults whose blood pressure stays high even when taking two or more other medications. Participants received either 1 mg, 2 mg, or a placebo for 12 weeks. The main goal was to see if baxdrostat could safely low…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase 3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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Health workers tackle social barriers to control diabetes and blood pressure
Disease control CompletedThis study tests whether community health workers (CHWs) who screen patients for social needs like food, housing, or transportation and connect them to resources can improve blood sugar and blood pressure control. About 3,120 adults with uncontrolled diabetes or hypertension from…
Matched conditions: UNCONTROLLED HYPERTENSION
Sponsor: Morehouse School of Medicine • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Zapping kidney nerves may tame tough blood pressure
Disease control CompletedThis study tested a device that uses ultrasound to calm overactive nerves in the kidneys, which can drive high blood pressure. Researchers enrolled 44 people with stage 3 chronic kidney disease and uncontrolled hypertension. Half received the real procedure, half a sham, to see i…
Matched conditions: UNCONTROLLED HYPERTENSION
Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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New pill may help when blood pressure meds aren't enough
Disease control CompletedThis study tested a new drug called baxdrostat in 326 adults whose high blood pressure was not controlled even with two or more medications. Participants took either 1 mg, 2 mg of baxdrostat, or a placebo daily for 12 weeks. The main goal was to see if baxdrostat could lower syst…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase 3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Ear device zaps nerves to tame stubborn high blood pressure?
Disease control CompletedThis pilot study tested a device that sends mild electrical pulses to a nerve in the ear, aiming to lower blood pressure in people whose hypertension is not controlled by medication. 63 adults took part, and the device was compared to a sham (fake) version. The goal was to see if…
Matched conditions: UNCONTROLLED HYPERTENSION
Sponsor: Queen Mary University of London • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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New blood pressure Drug's safety checked in cortisol study
Knowledge-focused CompletedThis study tested whether baxdrostat, an experimental drug for high blood pressure, affects the body's stress hormone cortisol. 48 adults with uncontrolled hypertension took baxdrostat or a placebo for 8 weeks. Researchers measured cortisol levels before and after a stimulation t…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase 2 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC