UNCONTROLLED HYPERTENSION
Clinical trials for UNCONTROLLED HYPERTENSION explained in plain language.
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Kidney nerve zapping shows promise for tough blood pressure in kidney disease
Disease control CompletedThis study tested a procedure called renal denervation, which uses energy to calm overactive nerves in the kidneys, to see if it could lower blood pressure in people with chronic kidney disease (stage 3) whose blood pressure remained high despite taking 1-5 medications. 44 partic…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: NA • Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Disease control
Last updated May 26, 2026 11:01 UTC
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Zapping a nerve to tame stubborn high blood pressure?
Disease control CompletedThis pilot study tested a non-invasive device that stimulates a nerve in the neck to see if it can safely lower blood pressure in 63 adults whose high blood pressure was not controlled by medication. Participants received either the real stimulation or a sham (fake) treatment. Th…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: NA • Sponsor: Queen Mary University of London • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New pill could help when blood pressure meds Aren't enough
Disease control CompletedThis study tested a new drug called baxdrostat in 326 adults whose high blood pressure remains uncontrolled despite taking two or more medications, including some with resistant hypertension. The goal was to see if adding baxdrostat lowers blood pressure more than a placebo after…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 22, 2026 13:55 UTC
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New pill may help when blood pressure meds aren't enough
Disease control CompletedThis study tested a new drug called baxdrostat in about 800 adults with high blood pressure that remains high despite taking two or more medications. Participants took either 1 mg, 2 mg, or a placebo pill daily for 12 weeks. The goal was to see if baxdrostat could safely lower bl…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 12, 2026 13:41 UTC
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Blood pressure Drug's hidden effect on stress hormone revealed
Knowledge-focused CompletedThis study looked at whether baxdrostat, a new drug for high blood pressure, changes how the body makes cortisol (a stress hormone). 48 adults with uncontrolled high blood pressure took baxdrostat or a placebo for 8 weeks. Researchers measured cortisol levels before and after a s…
Matched conditions: UNCONTROLLED HYPERTENSION
Phase: PHASE2 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated May 26, 2026 11:04 UTC