Treatment-resistant major depressive disorder
Clinical trials for Treatment-resistant major depressive disorder explained in plain language.
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Sound waves to lift mood? new study tests ultrasound for depression
Symptom relief OngoingThis study tests a new, non-invasive brain stimulation method using low-intensity ultrasound waves aimed at specific brain areas linked to depression. Researchers will personalize the treatment for each of the 30 participants based on their brain scans. The goal is to see if this…
Matched conditions: TREATMENT-RESISTANT MAJOR DEPRESSIVE DISORDER
Phase 1/2 • Sponsor: Brian Mickey • Aim: Symptom relief
Last updated Sep 10, 2026 00:00 UTC
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Brain zaps for depression? tiny study hopes to lift the fog
Symptom relief OngoingThis small pilot study tests whether deep brain stimulation (DBS) aimed at a specific brain region called the lateral habenula can safely reduce symptoms in 6 adults with severe, treatment-resistant depression. Participants have either major depressive disorder or bipolar I and h…
Matched conditions: TREATMENT-RESISTANT MAJOR DEPRESSIVE DISORDER
Sponsor: Wayne Goodman MD • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC