Total knee arthroplasty (postoperative pain)
Clinical trials for Total knee arthroplasty (postoperative pain) explained in plain language.
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Electric brain zaps and mind tricks: a new combo to fight Post-Surgical pain?
Symptom relief CompletedThis trial tests whether a gentle electrical brain stimulation technique called tDCS, combined with a cognitive-behavioral intervention (CBI), can reduce pain and opioid use in veterans after knee or hip replacement surgery. Participants receive either tDCS, CBI, both, or a place…
Matched conditions: TOTAL KNEE ARTHROPLASTY (POSTOPERATIVE PAIN)
Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Aug 22, 2026 00:00 UTC
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New combo approach may ease pain after knee surgery
Symptom relief CompletedThis completed study looked at whether adding a continuous nerve block (fascia iliaca compartment block) to a standard joint injection can better control pain after total knee replacement. Researchers reviewed records of 60 patients to compare pain scores and satisfaction. The go…
Matched conditions: TOTAL KNEE ARTHROPLASTY (POSTOPERATIVE PAIN)
Sponsor: Kırıkkale University • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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New implant could ease pain after knee replacement, reduce opioid use
Symptom relief CompletedThis phase 2 trial tested an experimental implant called ATX101 that slowly releases the numbing drug bupivacaine into the knee after total knee replacement surgery. The study involved 226 adults and compared ATX101 to a saline placebo and standard bupivacaine injections. The goa…
Matched conditions: TOTAL KNEE ARTHROPLASTY (POSTOPERATIVE PAIN)
Phase 2 • Sponsor: Allay Therapeutics, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC