TDP-43 proteinopathies
Clinical trials for TDP-43 proteinopathies explained in plain language.
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Can a new PET tracer light up the protein behind some dementias and ALS?
Diagnosis Recruiting nowThis early-phase trial is testing whether an experimental imaging agent called [18F]ACI-19626 can safely and reliably detect abnormal clumps of a protein called TDP-43 in the brain using PET scans. TDP-43 buildup is linked to certain forms of dementia, such as frontotemporal deme…
Matched conditions: TDP-43 PROTEINOPATHIES
Early phase 1 • Sponsor: AC Immune SA • Aim: Diagnosis
Last updated Aug 28, 2026 00:00 UTC
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Breathing support in ALS: what it means for patients and families
Knowledge-focused Recruiting nowALS is a rapidly progressive nerve disease with no cure, and extending breathing support into later stages raises hard questions about quality of life. Researchers in Norway are following 200 ALS patients, their partners and their children with questionnaires before and after lon…
Matched conditions: TDP-43 PROTEINOPATHIES
Sponsor: Haukeland University Hospital • Aim: Knowledge-focused
Last updated Sep 21, 2026 21:00 UTC
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AI hunts for early clues to Parkinson's and Alzheimer's progression
Knowledge-focused Recruiting nowThis study follows 600 people with neurodegenerative diseases such as Parkinson's, Alzheimer's, and related conditions over 1 to 10 years. Researchers collect data from routine clinical exams, brain imaging, movement analysis, and blood tests. They use statistical tools and artif…
Matched conditions: TDP-43 PROTEINOPATHIES
Sponsor: Casa di Cura San Raffaele Cassino • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC