T2DM
Clinical trials for T2DM explained in plain language.
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New drug cocktail aims to tackle diabetes and fatty liver together
Disease control Not yet recruitingThis study tests whether adding alogliptin to two common diabetes drugs (pioglitazone and metformin) works better than the two-drug combination alone for people with type 2 diabetes who also have fatty liver disease. The goal is to improve blood sugar control, fat levels, and pan…
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated May 26, 2026 11:25 UTC
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Diabetes drug semaglutide under scrutiny for bone risks
Disease control Not yet recruitingThis study looks at whether semaglutide, a common diabetes drug, affects bone density and fracture risk in people with type 2 diabetes. About 150 adults aged 50-75 with low bone mass or a recent fracture will take either semaglutide plus metformin or metformin alone for 12 months…
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated May 26, 2026 11:18 UTC
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New drug aims to protect kidneys in diabetes patients
Disease control Not yet recruitingThis study tests whether the investigational drug HTD1801 can slow kidney damage in adults with both type 2 diabetes and chronic kidney disease. About 75 participants will receive either HTD1801 or a placebo twice daily for 12 weeks. The main goal is to see if the drug reduces pr…
Matched conditions: T2DM
Phase: PHASE2 • Sponsor: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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New diabetes drug HM15275 enters Mid-Stage trial
Disease control Not yet recruitingThis study tests a new medicine called HM15275 for people with type 2 diabetes. About 180 adults who manage their diabetes with diet and exercise or metformin will receive either the drug or a placebo for 36 weeks. The main goal is to see if the drug improves blood sugar control,…
Matched conditions: T2DM
Phase: PHASE2 • Sponsor: Hanmi Pharmaceutical Company Limited • Aim: Disease control
Last updated May 11, 2026 20:54 UTC
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Sleep and menopause may harm diabetic women's hearts, study warns
Knowledge-focused Not yet recruitingThis study looks at how menopause and poor sleep change heart structure and function in women aged 48-58 with type 2 diabetes. Researchers will use heart ultrasounds to measure early signs of heart strain. No treatment is given; the goal is to better understand these risks.
Matched conditions: T2DM
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated May 18, 2026 12:04 UTC