Stage IV prostate cancer
Clinical trials for Stage IV prostate cancer explained in plain language.
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Can radiation boost a personalized prostate cancer vaccine?
Disease control CompletedResearchers are testing whether giving radiation therapy before sipuleucel-T, a personalized immunotherapy vaccine, works better than the vaccine alone in men with hormone-resistant prostate cancer that has spread. The trial enrolls about 51 participants and randomly assigns them…
Matched conditions: STAGE IV PROSTATE CANCER
Phase 2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Old drug, new hope: niclosamide combo tackles tough prostate cancer
Disease control CompletedThis early-stage trial tested the safety and best dose of adding niclosamide (a drug used for tapeworm infections) to standard hormone therapy (enzalutamide) in 6 men with advanced prostate cancer that no longer responds to hormone treatment. The goal was to see if the combinatio…
Matched conditions: STAGE IV PROSTATE CANCER
Phase 1 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New radiation approach targets multiple tumors at once in early trial
Knowledge-focused CompletedThis early-phase trial tested a precise, high-dose radiation technique called stereotactic body radiotherapy (SBRT) in 42 patients with breast, lung, or prostate cancer that had spread to several places in the body. The main goal was to find the safest dose and check for side eff…
Matched conditions: STAGE IV PROSTATE CANCER
Phase 1 • Sponsor: NRG Oncology • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Glow-in-the-Dark antibody could help surgeons spot prostate cancer
Knowledge-focused CompletedThis early-phase trial tested a fluorescent antibody that attaches to prostate cancer cells. Seven men with moderate- to high-risk prostate cancer received the antibody before robotic prostate removal surgery. The goal was to see if the glowing antibody could help surgeons identi…
Matched conditions: STAGE IV PROSTATE CANCER
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC