STAGE III BLADDER UROTHELIAL CARCINOMA AJCC V6 AND V7
Clinical trials for STAGE III BLADDER UROTHELIAL CARCINOMA AJCC V6 AND V7 explained in plain language.
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New drug targets genetic weakness in bladder cancer
Disease control OngoingThis phase 2 trial tests a drug called sapanisertib in 17 people with advanced bladder cancer that has a specific genetic change (TSC1 or TSC2 mutation). The drug works by blocking a protein that helps cancer cells grow. Researchers want to see if the drug can shrink tumors and h…
Matched conditions: STAGE III BLADDER UROTHELIAL CARCINOMA AJCC V6 AND V7
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 23, 2026 12:09 UTC
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Immune drug aims to stop bladder cancer return after surgery
Disease control OngoingThis phase 3 trial tests whether the immune-boosting drug pembrolizumab can help prevent bladder cancer from coming back after surgery. About 739 patients with muscle-invasive or locally advanced urothelial cancer will receive either pembrolizumab or just observation. The study m…
Matched conditions: STAGE III BLADDER UROTHELIAL CARCINOMA AJCC V6 AND V7
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 23, 2026 11:56 UTC
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Immunotherapy combo shows promise for bladder cancer patients unable to get chemo
Disease control OngoingThis early-phase trial is testing whether giving two immunotherapy drugs (durvalumab and tremelimumab) before surgery can help patients with aggressive bladder cancer who cannot take standard chemotherapy. The study involves 54 participants and primarily looks at safety and how t…
Matched conditions: STAGE III BLADDER UROTHELIAL CARCINOMA AJCC V6 AND V7
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 23, 2026 11:55 UTC