SOLID NEOPLASM
Clinical trials for SOLID NEOPLASM explained in plain language.
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New combo therapy aims to zap spine tumors before they paralyze
Disease control OngoingThis study tests whether using heat (thermal ablation) followed by very precise radiation (stereotactic radiosurgery) can better control cancer that has spread to the spine and is pressing on the spinal cord. About 60 adults with various solid tumors (like lung, breast, or prosta…
Matched conditions: SOLID NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 09:25 UTC
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New hope for kids with rare cancers: drug blocks tumor growth
Disease control OngoingThis study tests a daily pill called cabozantinib in children and young adults (up to age 30) with rare cancers like sarcomas, Wilms tumor, and others that have come back or not responded to treatment. The drug works by blocking signals that help tumors grow and form blood vessel…
Matched conditions: SOLID NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 08:19 UTC
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Experimental combo targets tough cancers in early trial
Disease control OngoingThis early-phase study tests a new drug called veliparib combined with two chemotherapy drugs (cyclophosphamide and doxorubicin) in people with advanced solid tumors or non-Hodgkin lymphoma that has spread or can't be removed by surgery. The main goal is to find the safest dose a…
Matched conditions: SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New drug shows promise for rare childhood cancers
Disease control OngoingThis study tests a drug called larotrectinib in children and young adults up to age 30 who have certain cancers (solid tumors or leukemia) with a specific genetic change called a TRK fusion. The goal is to see if the drug can shrink tumors or control the cancer. About 33 particip…
Matched conditions: SOLID NEOPLASM
Phase: PHASE2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Tailoring cancer drug doses: a step toward smarter treatment
Disease control OngoingThis study tests whether adjusting the dose of the drug pazopanib based on individual patient blood levels can improve treatment for people with advanced solid tumors that have not responded to standard therapies. About 54 participants will receive different doses and diets to fi…
Matched conditions: SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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New drug duo targets Hard-to-Treat brain tumors
Disease control OngoingThis early-phase trial tests a new drug (MLN0128) combined with bevacizumab in people with recurrent glioblastoma (a brain cancer) or other advanced solid tumors that have stopped responding to standard treatments. The main goals are to find the safest dose and understand side ef…
Matched conditions: SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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Simple Check-Up may predict chemo risks in older cancer patients
Knowledge-focused OngoingThis study looks at whether a special health check-up (geriatric assessment) for older adults with solid tumors can help predict serious side effects from chemotherapy. About 600 participants will be evaluated for things like daily function, other health problems, mood, social su…
Matched conditions: SOLID NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Cancer testing study pulled before it started
Knowledge-focused TerminatedThis study was designed to look at how community cancer clinics test for biomarkers in common cancers like lung, breast, and colorectal cancer. The goal was to find out if testing is fast and accurate, and to spot any differences in how tests are done. However, the study was with…
Matched conditions: SOLID NEOPLASM
Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated May 18, 2026 12:10 UTC