Severe aplastic anemia (SAA)
Clinical trials for Severe aplastic anemia (SAA) explained in plain language.
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Can a Three-Drug combo shield stem cell transplant patients from a dangerous immune attack?
Disease control Not yet recruitingThis trial tests a combination of sirolimus, ruxolitinib, and mycophenolate mofetil to prevent acute graft-versus-host disease (aGVHD) in patients receiving a half-matched stem cell transplant. The study focuses on patients with blood cancers or severe aplastic anemia who cannot …
Matched conditions: SEVERE APLASTIC ANEMIA (SAA)
Phase 1/2 • Sponsor: Peking University People's Hospital • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Experimental drug targets bone marrow failure
Disease control Not yet recruitingThis study tests an experimental drug called dibotatug (DR-01) in adults with bone marrow failure syndromes, including severe aplastic anemia. The goal is to see if the drug is safe and can improve blood cell counts. Participants receive dibotatug by IV infusion, and researchers …
Matched conditions: SEVERE APLASTIC ANEMIA (SAA)
Phase 1/2 • Sponsor: Dren Bio • Aim: Disease control
Last updated Jul 26, 2026 00:00 UTC
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New drug cocktail aims to free aplastic anemia patients from transfusions
Disease control Not yet recruitingThis phase 2 trial tests a combination of three drugs—cyclosporine, a thrombopoietin receptor agonist (eltrombopag or hetrombopag), and romiplostim—in 43 adults newly diagnosed with severe aplastic anemia or transfusion-dependent non-severe aplastic anemia. The goal is to see if …
Matched conditions: SEVERE APLASTIC ANEMIA (SAA)
Phase 2 • Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC