SCLC, EXTENSIVE STAGE
Clinical trials for SCLC, EXTENSIVE STAGE explained in plain language.
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Cancer-Fighting virus joins chemo in new hope for tough lung cancer
Disease control Recruiting nowThis study tests a new treatment for advanced small cell lung cancer that has come back or not responded to standard platinum chemotherapy. The treatment combines an oncolytic virus (Olvi-Vec) with standard chemotherapy drugs. The goal is to see if this combination is safe and ca…
Matched conditions: SCLC, EXTENSIVE STAGE
Phase: PHASE1, PHASE2 • Sponsor: Newsoara HYK Biopharmaceutical (Shanghai) Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 08:46 UTC
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New daily pill shows promise for tough cancers
Disease control Recruiting nowThis study tests a new daily pill, ABP1011T, in people with advanced solid tumors like small cell lung cancer, esophageal cancer, and others that have stopped responding to standard treatments. About 110 participants will take one tablet each day on an empty stomach in 21-day cyc…
Matched conditions: SCLC, EXTENSIVE STAGE
Phase: PHASE2 • Sponsor: Shanghai AB PharmaTech Ltd. • Aim: Disease control
Last updated May 26, 2026 08:44 UTC
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New combo therapy aims to extend life for aggressive lung cancer patients
Disease control Recruiting nowThis study tests whether adding golidocitinib to standard PD-1 inhibitor maintenance therapy can help keep extensive-stage small cell lung cancer from progressing. About 20 adults with untreated advanced disease will receive the combination after initial chemo. The goal is to see…
Matched conditions: SCLC, EXTENSIVE STAGE
Phase: PHASE2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated May 26, 2026 08:32 UTC
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New drug combo aims to stall lung cancer progression
Disease control Recruiting nowThis study tests whether combining adebrelimab (an immunotherapy) with etoposide capsules can help keep extensive-stage small cell lung cancer from growing after initial chemotherapy. About 32 adults who have not worsened after standard induction therapy will receive the combinat…
Matched conditions: SCLC, EXTENSIVE STAGE
Phase: PHASE2 • Sponsor: Tang-Du Hospital • Aim: Disease control
Last updated May 26, 2026 08:31 UTC
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Engineered immune cells take on hard-to-treat lung cancer
Disease control Recruiting nowThis study tests a new treatment using specially designed immune cells (CAR-NK cells) that target two markers on small cell lung cancer cells. The goal is to find a safe dose and see if these cells can shrink tumors in adults whose cancer has returned or not responded to standard…
Matched conditions: SCLC, EXTENSIVE STAGE
Phase: PHASE1, PHASE2 • Sponsor: Beijing Biotech • Aim: Disease control
Last updated May 26, 2026 08:29 UTC
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New hope for tough lung cancer: targeted radiation plus immunotherapy tested as maintenance
Disease control Recruiting nowThis early-phase study tests a new combination treatment for people with extensive-stage small cell lung cancer (ES-SCLC) whose tumors have a specific marker (SSTR). After completing standard first-line therapy, participants will receive a targeted radioactive drug ([225Ac]Ac-DOT…
Matched conditions: SCLC, EXTENSIVE STAGE
Phase: PHASE1 • Sponsor: Peking University Cancer Hospital & Institute • Aim: Disease control
Last updated May 26, 2026 08:19 UTC
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New hope for aggressive lung cancer: targeted drug combo aims to stall progression
Disease control Recruiting nowThis study tests whether adding the drug niraparib to standard maintenance therapy can help control extensive-stage small cell lung cancer in people whose tumors have a specific marker (SLFN11-positive). About 44 participants will take a daily niraparib pill along with an anti-PD…
Matched conditions: SCLC, EXTENSIVE STAGE
Phase: PHASE2 • Sponsor: ETOP IBCSG Partners Foundation • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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Promising new scan may spot lung cancer more precisely
Diagnosis Recruiting nowThis study tests a new radioactive probe called PFD3 that targets a protein (DLL3) found on small cell lung cancer cells. Using PET/CT scans, doctors hope to see tumors more clearly and assess the cancer's spread. About 30 adults with confirmed small cell lung cancer will receive…
Matched conditions: SCLC, EXTENSIVE STAGE
Phase: PHASE1, PHASE2 • Sponsor: Peking University First Hospital • Aim: Diagnosis
Last updated May 15, 2026 11:53 UTC