SARS-CoV-2
Clinical trials for SARS-CoV-2 explained in plain language.
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COVID vaccine trial for babies halted early – Here's what we know
Vaccine Stopped earlyThis study looked at whether the mRNA-1273.214 COVID-19 vaccine is safe and works in infants as young as 12 weeks to under 6 months old. It was a small, early-stage trial that was stopped before completion. The main goal was to check for side effects like fever, fussiness, and in…
Matched conditions: SARS-COV-2
Phase 2 • Sponsor: ModernaTX, Inc. • Aim: Vaccine
Last updated Jun 27, 2026 08:00 UTC
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COVID-19 antibody drug trial halted early — little data to show
Disease control Stopped earlyThis early-stage study tested a new antibody drug (REGN14256) alone or with imdevimab in 25 adults with mild COVID-19 and no risk factors for severe illness. The goal was to check safety and whether the drug could lower virus levels. However, the trial was terminated early, so we…
Matched conditions: SARS-COV-2
Phase 1/2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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HIV drug fails to prove COVID-19 prevention in abandoned trial
Prevention Stopped earlyThis study tested whether a daily pill used for HIV (TAF/FTC) could prevent COVID-19 in healthcare workers at high risk of exposure. Over 1,300 workers were randomly assigned to get the drug or a placebo for 12 weeks. The trial was stopped early, so it's unclear if the drug had a…
Matched conditions: SARS-COV-2
Phase 3 • Sponsor: Hospital Italiano de Buenos Aires • Aim: Prevention
Last updated Jun 26, 2026 14:58 UTC
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Pfizer mines insurance data to see if its vaccine stops long COVID
Knowledge-focused Stopped earlyThis study looks at anonymous health records from California and Louisiana to see if the Pfizer-BioNTech COVID-19 vaccine helps prevent post-COVID conditions (long COVID). Researchers will also track who gets vaccinated. The study includes adults with a COVID-19 diagnosis between…
Matched conditions: SARS-COV-2
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Sep 17, 2026 00:00 UTC
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COVID-19 may harm the brain in ways scans Can't see
Knowledge-focused Stopped earlyThis study looked for hidden brain damage in 38 hospitalized COVID-19 patients. Instead of using standard MRI scans, researchers used electrical tests to check how well the brainstem was working. The goal was to find subtle nervous system problems that might not show up on regula…
Matched conditions: SARS-COV-2
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC