Rheumatic heart disease in children
Clinical trials for Rheumatic heart disease in children explained in plain language.
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Can two existing drugs stop rheumatic fever from scarring young hearts?
Disease control Not yet recruitingResearchers are running a Phase 3 trial to see whether hydroxychloroquine or corticosteroids can reduce heart valve damage in children and young people with acute rheumatic fever. The trial enrolls about 600 participants aged 4 to 25 who are hospitalized with confirmed valve infl…
Matched conditions: RHEUMATIC HEART DISEASE IN CHILDREN
Phase 3 • Sponsor: Starship Child Health, Te Toka Tumai Auckland • Aim: Disease control
Last updated Sep 21, 2026 17:00 UTC
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Community health workers may boost antibiotic adherence for rheumatic heart disease
Disease control Not yet recruitingThis study tests whether community health workers (CHWs) can help people with rheumatic heart disease (RHD) take their monthly antibiotic shots consistently. The trial will enroll about 308 participants in Brazil and Timor-Leste, including adults and children with RHD and their c…
Matched conditions: RHEUMATIC HEART DISEASE IN CHILDREN
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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A simple antibiotic may shield children from heart disease
Prevention Not yet recruitingThis trial tests whether giving children aged 5 to 8 a twice-daily penicillin pill can prevent rheumatic heart disease, a serious condition that can damage heart valves. Researchers will compare children who take the antibiotic with those who do not, following them for three year…
Matched conditions: RHEUMATIC HEART DISEASE IN CHILDREN
Phase 3 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Prevention
Last updated Sep 05, 2026 00:00 UTC
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Can yearly heart scans catch rheumatic disease early in children?
Knowledge-focused Not yet recruitingThis study follows 7,500 children aged 5 to 8 who live in areas where rheumatic heart disease is common. Each child gets a heart ultrasound once a year for three years to check for early signs of the disease. Researchers will count how many children develop rheumatic heart diseas…
Matched conditions: RHEUMATIC HEART DISEASE IN CHILDREN
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Aug 29, 2026 00:00 UTC